Drugsafety – Antihistamin

DAFTAR OBAT AMAN DAN BERBAHAYA UNTUK IBU HAMIL DAN MENYUSUI

Antihistamin

Nama Obat

AAP
approved?*

Risiko Menyusui**

Brompheniramine

not reviewed

L3 (moderately safe)

Chlorpheniramine (Chlor-Trimeton) CTM

not reviewed

L3 (moderately safe)

Cetirizine (Zyrtec)

not reviewed

L2 (safer)

Dexbrompheniramine maleate
with d-isoephedrine

yes

not reviewed

Diphenhydramine (Benadryl)

not reviewed

L2 (safer)

Doxylamine

not reviewed

L4 (possibly hazardous)

Fexofenadine (Allegra)

yes

L3 (moderately safe)

Loratadine (Claritin)

yes

L2 (safer)

Terfenadine (Seldane)

yes

not reviewed

Triprolidine (Actidil, Actifed)

yes

L1 (safest)

*  Per the AAP Policy Statement The Transfer of Drugs and Other Chemicals Into Human Milk, revised September 2001.

      • Approved: (Table 6) Maternal Medication Usually Compatible With Breastfeeding
      • Concern: (Table 4) Drugs for Which the Effect on Nursing Infants Is Unknown but May Be of Concern
      • Caution: (Table 5) Drugs That Have Been Associated With Significant Effects on Some Nursing Infants and Should Be Given to Nursing Mothers With Caution
      • NR: Not Reviewed. This drug has not yet been reviewed by the AAP.

** Per Medications’ and Mothers’ Milk by Thomas Hale, PhD (2004 edition).

 Lactation Risk Categories  Pregnancy Risk Categories
  • L1 (safest)
  • L2 (safer)
  • L3 (moderately safe)
  • L4 (possibly hazardous)
  • L5 (contraindicated)
  • A (controlled studies show no risk)
  • B (no evidence of risk in humans)
  • C (risk cannot be ruled out)
  • D (positive evidence of risk)
  • X (contraindicated in pregnancy)
NR: Not Reviewed. This drug has not yet been reviewed by Hale.

Posted on 27 Desember 2012, in Drug List and tagged . Bookmark the permalink. Tinggalkan komentar.

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